if not ImageEnView1.Selected then
    exit;

  ImageEnView1.LayersCurrent := 1;
  idx := ImageEnView1.LayersCreateFromSelection;
  ImageEnView1.Deselect;

  ImageEnView1.Proc.HistAutoEqualize();
  ImageEnView1.Proc.Negative;
  ImageEnView1.Proc.ConvertToGray;
  ImageEnView1.CurrentLayer.Operation := TIERenderOperation(4);

  ImageEnView1.LayersMerge(1,idx, True);

• Load an Image/Photo
• Select an area
• Click on button: Create Mask From Selection
• Once the loaded image/photo is masked
• Select something outside of the visible mask area
• Click on button: Add Selection To Mask

  ImageEnView1.Layers[1].Bitmap.PixelFormat := ie24rgb;
  ImageEnView1.Layers[1].IsMask := False;
  ImageEnView1.LayersMerge(1, 2, True);
  ImageEnView1.Layers[1].IsMask := True;
  ImageEnView1.Layers[1].Visible := False;